Little Sister Savior

The player has completed the game without harvesting any Little Sisters

Defeated Atlas

The player has defeated Atlas

Became a Big Daddy

The player has become a Big Daddy

Ammo Inventor

The player has successfully invented all possible ammo types

Dealt with every Little Sister

The player has either Harvested or Rescued every possible Little Sister

Five Fully Upgraded Weapons

Fully upgrade five weapons

Tonic Collector

Collect or Invent 58 Tonics in the Physical, Engineering and Combat tracks

Four Fully Upgraded Weapons

Fully upgrade four weapons

Fully Researched Thug Splicer

The player has fully researched the Thuggish Splicer

Three Fully Upgraded Weapons

The player has fully upgraded three weapons

Maxed All Tracks

Purchased every slot in all four Plasmid and Tonic tracks

Broke Fontaine's Mind Control

The player has broken Fontaine's mind control

Fully Researched Gun Splicer

The player has fully researched the Leadhead Splicer

Two Fully Upgraded Weapons

The player has fully upgraded two weapons

Defeated Andrew Ryan

The player has defeated Andrew Ryan

Irony

The player has taken a picture of Sander Cohen's corpse

Completed Cohen's Masterpiece

The player has completed Sander Cohen's great masterpiece

Fully Researched Spider Splicer

The player has fully researched the Spider Splicer

Restored the Forest

The player has restored the forests of Arcadia

Maxed One Track

The player has purchased every slot in one of the Plasmid or Tonic tracks

One Fully Upgraded Weapon

The player has fully upgraded one weapon

Basic Inventor

The player has successfully invented at least one item

Upgraded a Weapon

The player has acquired at least one weapon upgrade

Defeated Peach Wilkins

The player has defeated Peach Wilkins

Skilled Hacker

The player has successfully completed 50 hacks

Quality Research Photo

The player has taken a Research Photo of the highest grade

Researched a Splicer

The player has taken at least one Research Photo of a Splicer

Bought One Slot

The player has purchased one slot in any Plasmid or Tonic track

Defeated Dr. Steinman

The player has defeated the crazed Dr. Steinman

Hacked a Safe

The player has successfully hacked a safe

Hacked a Security Camera

The player has successfully hacked a security camera

Hacked a Vending Machine

The player has successfully hacked a vending machine

Hacked a Turret

The player has successfully hacked a turret

One Successful Hack

The player has performed at least one successful hack

Hacked a Security Bot

The player has successfully hacked a security bot

Completed Welcome

The player has successfully completed the Welcome To Rapture Level

Toaster in the Tub

The player has shocked an enemy in the water